Research Articles
Mastering Crystal Structure Prediction: Global Optimization Strategies for Drug Discovery and Materials Science
This article provides a comprehensive guide to global optimization methods for crystal structure prediction (CSP), tailored for researchers and industry professionals.
Navigating the Energy Landscape: A Comprehensive Guide to Global Minimum Search Algorithms for Molecular Conformation
This article provides a comprehensive overview of global minimum search algorithms crucial for determining the stable three-dimensional structures of molecules, a fundamental problem in computational chemistry and drug discovery.
Evolving Molecules: How Genetic Algorithms Are Revolutionizing Chemical Space Exploration in Drug Discovery
This article provides a comprehensive guide to genetic algorithms (GAs) for navigating the vastness of chemical space, tailored for researchers, scientists, and drug development professionals.
Predicting Protein & Nanoparticle Clusters with Genetic Algorithms: A Guide for Computational Researchers
This comprehensive guide explores the implementation of genetic algorithms (GAs) for predicting the stable structures of molecular and nanoscale clusters—a critical challenge in drug development and materials science.
Paired Imaging Strategies: Optimizing Gadolinium-Based Contrast Agent Protocols for Advanced Biomedical Research
This article provides a comprehensive analysis of gadolinium-based contrast agents (GBCAs) in paired imaging methodologies, targeting researchers and drug development professionals.
Absolute Quantification of Glycans: A Comprehensive Guide to the Full Glycome Internal Standard Approach for MALDI-TOF-MS
This article provides a comprehensive guide for researchers and drug development professionals on implementing a full glycome internal standard approach for accurate, absolute quantification of glycans using MALDI-TOF-MS.
Implementing Particle Swarm Optimization in Fortran for Biomolecular Cluster Energy Minimization: A Computational Chemistry Guide
This article provides a comprehensive guide for researchers and computational scientists on implementing Particle Swarm Optimization (PSO) in modern Fortran for the challenging task of global optimization of molecular cluster...
FRAP Fluorescence Recovery: Measuring Biomolecular Condensate Dynamics for Drug Discovery
This article provides a comprehensive guide to Fluorescence Recovery After Photobleaching (FRAP) for quantifying the dynamic properties of biomolecular condensates.
Measuring Phase Separation: A Comprehensive FRAP Analysis Guide for Biomolecular Condensate Dynamics
This article provides a detailed guide to Fluorescence Recovery After Photobleaching (FRAP) for quantifying the material properties and dynamics of biomolecular condensates.
Unlocking Neutrophil Defense: The Critical Role of FES Kinase in Phagocytosis and Immune Regulation
This comprehensive review synthesizes current research on the non-receptor tyrosine kinase FES (Feline Sarcoma) and its pivotal function in neutrophil-mediated phagocytosis.